Blind, Lame, Deaf, Poor

In spiritual significance, the blind receiving sight is also first. In the Lord's salvation He first opens our eyes (Acts 26:18). Then we can receive Him and walk to follow Him.
The lame signifies those who cannot walk in God's way. After being saved, the lame can walk by new life (John 5:8-9).
The deaf signifies those who cannot hear God. After being saved, they can hear the Lord's voice (John 10:27). The dead signifies those who are dead in sins (Eph. 2:1,
5), unable to contact God. After being regenerated, they can fellowship with God with their regenerated spirit.
The poor signifies everyone without Christ, without God, who have no hope in the world (Eph. 2:12). Upon receiving the gospel, they are made rich in Christ (2 Cor. 8:9; Eph. 3:8).